Ask a doctor on the topic of Internal medicine

Rheumatism/Secondary Hyperparathyroidism/Vitamin D deficiency - unclear lab values

September 23, 2010 | 25,00 EUR | answered by Dr. med. Ralf Berg

Dear Sir or Madam,

I would like to ask you some questions regarding laboratory tests. I am a 51 year old female. Last week, Dr. Berg helped me here and is somewhat familiar with the medical history.

Latest diagnoses:
Secondary hyperparathyroidism due to vitamin D deficiency
Anxiety disorder and depression
2 splenic lesions (currently being investigated)
Steatosis hepatis (diagnosed when I was a young adult, I do not drink alcohol at all, have been slightly overweight for 2 years, previously always had a normal weight)

Laboratory:
Incidentally, antibodies against actin were found, investigation for ASMA
2/10 ASMA: atypical fluorescence pattern, investigation for vimentin (vimentin was not detected)

Hemostaseology:
Abnormal:
PTT 38.2 (22.5-35.7) elevated
Lupus ratio PTT 1.11 (above 1.07) elevated
Lupus anticoagulant index 36.88 (up to 15) elevated

Normal:
Kaolin clotting time
Quick (TPZ)
Thrombin time
Lupus anticoagulant
DRVVT Screen Lupus
IgG cardiolipin antibodies

QUESTIONS:
- What does the presence of ASMA, actin, vimentin, and the 3 elevated values in hemostaseology mean?
- Should I undergo further investigations, or is there no need for it?
- What does neuromuscular balance mean in relation to secondary hyperparathyroidism due to vitamin D deficiency?

Thank you in advance for your efforts and

kind regards.

Dr. med. Ralf Berg