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Occasional use of amyl nitrite, butyl nitrite, isobutyl nitrite - Poppers

Hello,

I occasionally (1x per week) use the so-called poppers (amyl nitrite, butyl nitrite, isobutyl nitrite) by inhaling two to three times from the bottle. My question is: are there any long-term impairments/damages associated with this frequency of use? If so, what are they?

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Uni-Arzt Freddy Feuerstein