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Which medications should I take to prevent malaria?

Dear doctor,

My name is Chloé Schlüter and I am planning a trip to a tropical country where malaria is prevalent. I am concerned about the prevention of malaria and wondering which medications I should take to protect myself effectively.

I am 28 years old, healthy, and have no known allergies or pre-existing conditions. I have already traveled to a malaria-endemic area where I took prophylaxis with Mefloquine. Unfortunately, I experienced strong side effects such as nightmares and dizziness, so I had to stop taking the medication.

Now I am unsure which medication I should take instead. I have heard of medications like Doxycycline and Atovaquone/Proguanil, but I am not sure which one is best suited for me. I want to be cautious and have effective prevention against malaria without risking strong side effects.

Can you please recommend which medication is best suited for me to protect myself from malaria? I want to feel safe during my trip and not take any health risks. Thank you in advance for your support and advice.

Sincerely,

Chloé Schlüter

Ralf Kock

Dear Chloé Schlüter,

Thank you for your inquiry regarding the prevention of malaria during your planned trip to a tropical country. It is understandable that you are concerned and seeking an effective prophylaxis that causes as few side effects as possible.

Since you have already experienced strong side effects such as nightmares and dizziness with Mefloquine, it is understandable that you are looking for alternative medications. In such cases, there are indeed other options that may be more suitable for you.

Doxycycline and Atovaquone/Proguanil are two common medications for malaria prevention. Doxycycline is an antibiotic that is also used to treat other infections. It is usually taken daily and should start at least one day before the trip and continue for four weeks after leaving the malaria area. Possible side effects of Doxycycline include gastrointestinal complaints, sensitivity to the sun, and fungal infections.

Atovaquone/Proguanil is a combination of two active ingredients that is also used for malaria prevention. It is usually taken daily and should start one day before the trip and continue for seven days after leaving the malaria area. Possible side effects include gastrointestinal complaints, headaches, and skin rashes.

Both medications have their pros and cons, and the choice often depends on individual factors such as possible allergies, pre-existing conditions, and personal preferences. Since you do not have any known allergies or pre-existing conditions, both Doxycycline and Atovaquone/Proguanil may be suitable for you.

It would be advisable to speak to your doctor to make an informed decision about which medication is best for you. Your doctor can better assess your individual situation and help you choose the appropriate medication. It is important that you also take other precautions against malaria during your trip, such as wearing long clothing, using mosquito nets, and insect repellents.

I hope this information helps you and wish you a safe and pleasant journey to the tropical country. If you have any further questions, I am at your disposal.

Kind regards,

Ralf Kock
Tropical Medicine Specialist

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