Ask a doctor on the topic of General medicine

Formation of bubbles

May 8, 2020 | 20,00 EUR | answered by Dr. med. Frauke Gehring

Hello Mrs. Gehring.. after a few weeks of more peace, unfortunately I am contacting you again... I have already reported several times about my mucosal lesions, which as I mentioned do not hurt. Also, due to lupus on the butterfly rash, I have been noticing for 1-2 years that blisters form in the mornings. After doing some research, I eventually found out that this is probably due to disturbed keratinocytes or something similar in lupus. Since it has been going on for quite some time, I am not worried about anything worse happening, and I don't have any severe clusters of large blisters anywhere.
But yesterday I had the feeling that something had bitten me on the arm, it suddenly started itching. Later also on my hip - all pretty normal so far. This morning I suddenly noticed strange little blisters on my arm (only on the itching spot), when I press on it, it is somewhat yellowish, there is nothing on my hip! Now I am worried again whether there might be some type of pemphigoid behind it, or even connected to a neoplasm, is that an exaggeration again?
There were already some redness on the arm anyway, I think due to lupus...
Perhaps you can reassure me a bit...
Greetings

Dr. med. Frauke Gehring

Hello,

I am glad that you have endured it for a few weeks now! On the other hand, I am surprised that you are thinking of pemphigoid when it comes to small localized blisters. Pemphigoid is widespread and is associated with much larger blisters!

Localized blisters occur with shingles (although not typically on the arm), as well as a skin reaction in lupus and as part of a bacterial, locally limited infection. I would suggest observing the situation and, if it does not heal quickly, showing it to a doctor. It does not fit at all with pemphigoid.

Sincerely, Dr. Gehring